What does the future of clinical trials and evidence-based medicine look like?

What does the future of clinical trials and evidence-based medicine look like?

In a recent perspective published in Nature Medicine, the researcher shared his vision and future perspectives for the domains of clinical research and evidence-based therapeutics. Background In recent times, advancements in technological wearables, machine learning, and data mining have initiated the transformation of evidence-based medical practices to revolutionize next-generation trials and treatments. Despite scientific advances in…

Therapeutic small molecule can restore visual functions after optic nerve injury

Therapeutic small molecule can restore visual functions after optic nerve injury

Traumatic injury to the brain, spinal cord and optic nerve in the central nervous system (CNS) are the leading cause of disability and the second leading cause of death worldwide. CNS injuries often result in a catastrophic loss of sensory, motor and visual functions, which is the most challenging problem faced by clinicians and research…

How salt appetite differs between males and females

How salt appetite differs between males and females

While many studies have examined male salt consumption behaviors, less research has examined how these behaviors may differ among female subjects. To this end, a recent Nutrients journal study reviews differences in salt intake based on sex. Background The innate appetite for salt among humans and animals is largely driven by the physiological need for sodium to…

Long-term deep meditation may help to regulate the gut microbiome for better health

Long-term deep meditation may help to regulate the gut microbiome for better health

Regular deep meditation, practiced for several years, may help to regulate the gut microbiome and potentially lower the risks of physical and mental ill health, finds a small comparative study published in the open access journal General Psychiatry. The gut microbes found in a group of Tibetan Buddhist monks differed substantially from those of their secular neighbors,…

Group-based CBT relieves psychological distress, improves quality of life in younger heart patients

Group-based CBT relieves psychological distress, improves quality of life in younger heart patients

Group therapy relieves psychological distress, improves quality of life and results in fewer readmissions for heart problems, according to a study published today in European Heart Journal, a journal of the European Society of Cardiology (ESC). Approximately 20% of all cardiac patients have signs of psychological distress, rising to one-third of employed patients. Psychological symptoms like palpitations…

Eating less may be a more effective weight management strategy than intermittent fasting

Eating less may be a more effective weight management strategy than intermittent fasting

The frequency and size of meals was a stronger determinant of weight loss or gain than the time between first and last meal, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association. According to the senior study author Wendy L….

Researchers uncover the secret to the health benefits of brown rice

Researchers uncover the secret to the health benefits of brown rice

Asian diets feature rice as a staple grain, contributing towards nearly 90% of the world’s rice consumption. Brown rice, in particular, is known to have several health benefits. As a regular addition to the diet, it can help reduce body weight, lower cholesterol, and suppress inflammation. The ability of brown rice to neutralize reactive oxygen…

What is the association between nitrite and nitrate exposure and type 2 diabetes?

What is the association between nitrite and nitrate exposure and type 2 diabetes?

In a recent study published in PLoS Medicine, researchers evaluated the association between nitrate and nitrite exposure and T2D (type 2 diabetes) development risks. Background Nitrites and nitrates are naturally occurring substances present in soil and water and are ingested frequently from diet and drinking water sources. In addition, the compounds are utilized as food additive…

Overweight people have a different vitamin D metabolism

Overweight people have a different vitamin D metabolism

Vitamin D is an essential macronutrient that is involved in several biological processes. Vitamin D production takes place endogenously as vitamin D3 (cholecalciferol) or is obtained from the diet or supplements as vitamin D2 (ergocalciferol) or vitamin D3. The role of vitamin D in preventing osteomalacia and rickets has already been established. In addition, recent…